Jon E Sprague Selected Research

N-Methyl-3,4-methylenedioxyamphetamine (MDMA)

1/2019	The influence of the host microbiome on 3,4-methylenedioxymethamphetamine (MDMA)-induced hyperthermia and vice versa.
1/2016	Potentiation of Ecstasy-induced hyperthermia and FAT/CD36 expression in chronically exercised animals.
8/2009	Pharmacodynamic characterization of insulin on MDMA-induced thermogenesis.
2/2009	The hyperthermia mediated by 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) is sensitive to sex differences.
3/2008	Influence of thyroid hormones on 3,4-methylenedioxymethamphetamine-induced thermogenesis and reinforcing strength in monkeys.
10/2007	Ambient temperature effects on 3,4-methylenedioxymethamphetamine-induced thermodysregulation and pharmacokinetics in male monkeys.
1/2007	Roles of norepinephrine, free Fatty acids, thyroid status, and skeletal muscle uncoupling protein 3 expression in sympathomimetic-induced thermogenesis.
4/2006	Hypothyroidism alters striatal dopamine release mediated by 3,4-methylenedioxymethamphetamine (MDMA, ecstasy).
11/2005	Toxin-induced hyperthermic syndromes.
6/2005	Carvedilol reverses hyperthermia and attenuates rhabdomyolysis induced by 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) in an animal model.

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Jon E Sprague Research Topics

Disease

19	Hyperthermia 01/2019 - 04/2003
4	Rhabdomyolysis 01/2020 - 06/2004
2	Hyperthyroidism 03/2008 - 01/2007
2	Hypothermia 10/2007 - 04/2003
2	Hypothyroidism 01/2007 - 04/2006
2	Neuroleptic Malignant Syndrome 03/2006 - 11/2005
1	Poisoning 03/2022
1	Substance-Related Disorders (Drug Abuse) 01/2022
1	Heroin Dependence (Heroin Abuse) 01/2021
1	Drug-Related Side Effects and Adverse Reactions 01/2020
1	Cocaine-Related Disorders (Cocaine Addiction) 01/2019
1	Parkinson Disease (Parkinson's Disease) 01/2019
1	Respiratory Insufficiency (Respiratory Failure) 02/2017
1	Body Temperature Changes 01/2016
1	Body Weight (Weight, Body) 01/2016
1	Psychotic Disorders (Schizoaffective Disorder) 05/2014
1	Hypertension (High Blood Pressure) 05/2014
1	Myocardial Infarction 05/2014
1	Tachycardia (Tachyarrhythmias) 05/2014
1	Insulin Resistance 08/2009
1	Malignant Hyperthermia 03/2006
1	Serotonin Syndrome (Syndrome, Serotonin) 11/2005
1	Abnormal Reflex (Hyperreflexia) 11/2005
1	Choriocarcinoma 08/2004
1	Memory Disorders (Memory Loss) 07/2003

Drug/Important Bio-Agent (IBA)

17	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 01/2019 - 04/2003
4	Synthetic CathinoneIBA 01/2019 - 05/2014
3	Dopamine (Intropin)FDA LinkGeneric 01/2021 - 04/2006
3	Sympathomimetics (Sympathomimetic Amines)IBA 01/2019 - 03/2006
3	SaltsIBA 11/2016 - 05/2014
3	Nonesterified Fatty Acids (NEFA)IBA 01/2016 - 08/2009
3	Mitochondrial Uncoupling ProteinsIBA 01/2016 - 05/2005
3	Creatine Kinase (Creatine Phosphokinase)IBA 06/2005 - 06/2004
2	phenethylamineIBA 01/2020 - 01/2018
2	PhenethylaminesIBA 01/2020 - 01/2016
2	Methamphetamine (Desoxyn)FDA LinkGeneric 01/2020 - 11/2005
2	methyloneIBA 01/2019 - 11/2016
2	BenzodiazepinesIBA 02/2017 - 11/2005
2	Carvedilol (Coreg)FDA LinkGeneric 11/2016 - 06/2005
2	Uncoupling Protein 3IBA 10/2011 - 01/2007
2	Serotonin (5 Hydroxytryptamine)IBA 03/2006 - 11/2005
2	Pharmaceutical PreparationsIBA 06/2005 - 07/2004
1	Fentanyl (Sublimaze)FDA LinkGeneric 03/2022
1	Indicators and Reagents (Reagents)IBA 03/2022
1	Bile Acids and Salts (Bile Acids)IBA 01/2019
1	Opioid Analgesics (Opioids)IBA 02/2017
1	Carisoprodol (Soma)FDA LinkGeneric 02/2017
1	mephedroneIBA 11/2016
1	Adrenergic Receptors (Adrenergic Receptor)IBA 11/2016
1	pyrrolidineIBA 01/2016
1	KetonesIBA 01/2016
1	sulfo-N-succinimidyl oleateIBA 01/2016
1	CD36 AntigensIBA 01/2016
1	Insulin (Novolin)FDA Link 08/2009
1	Glucose (Dextrose)FDA LinkGeneric 08/2009
1	CatecholaminesIBA 06/2005
1	Illicit Drugs (Recreational Drugs)IBA 05/2005
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 08/2004
1	Dantrolene (Dantrium)FDA LinkGeneric 07/2004
1	NitrogenIBA 06/2004
1	CreatinineIBA 06/2004
1	Urea (Carbamide)FDA LinkGeneric 06/2004

Therapy/Procedure

5	Induced Hyperthermia (Thermotherapy) 01/2020 - 06/2004
1	Pain Management 01/2022
1	Therapeutics 01/2019